Idea

How about a monument in space to our species. Earth facing.

At least to warn our successors, decended from insects or some hive organism I hope, of the folly of mastery of technology when neglecting other aspects of knowledge. You know, that a slightly sophisticated tool-using civilisation capable of reaching space had at least the foresight to warn successor organisms of similar sophistication of the folly of our approach.

Economics, politics, history, psychology, sociology, politics, education, parenting, etc.

Such brilliant masters of the plastic universe, such hopeless boobs at anything that fails to lend itself to statistical analysis and the scientific method.

Human minds, unable, or uninterested as no financial incentives exist, to generate a mathematics or other methods capable of modelling and describing, so that predictive outputs are possible, such complex systems as human behaviour. Whether in the individual or aggregate.

Even with economics, for which there is some would say an excess of mathematics and statistics amenable information.

Such hopeless branches of human knowledge. No real predictive power. So what use are they?

Lets put down physics, chemistry, engineering, process technology and organisational science, and lets pay attention to incorporating accounting for simple things to start.

Like externalities.

A term of economics, externalities are costs or benefits accruing to those outside the transaction involving the product or service. Such as air pollution, produced making or consuming the good, but not paid by the manufacturer or consumer.

Why you cannot in fact put a price on clean air.

And of course any attempt to do so results in a backlash, as in Australia and their carbon tax.

So the allocation of resources, and therefore in this economic system, there are other options after all – history has demonstrated that at least, how most of us spend most of our time, is determined by a system incapable of pricing or accounting for anything really important to us.

When was the last time you bought love?

What is the mechanism that determines what gets produced and sold? Why the price mechanism!

That’s right, that shiny icon, totem, pillar, whateverthefuckitis.

Measuring avarice on the one hand, and parsimony on the other.

Just what I want, greed and stinginess determine how I live, the future of the planet (here’s hoping), what gets mined, produced, how and where.

Really, this is it?! The limit of human imagination, ingenuity, creativity, bravery?!

We get to play out the string and the big idea of the greatest potential existential threat in our history is a collective indifference driven by the parochial, banal, insular, and close-minded.

Who cares if global warming is not all it’s billed. We cannot reasonably know that, so saying this is crowd wisdom is bullshit.

Life is a game of percentages, we are not playing the percentages.

Relative risk.

It applies to our products. Do you want to risk something that the experts say has extremely low risk, or a novel chemical delivered as a drug? The price of remaining ill through trying nothing. Interesting that both issues involve the costs of environmental degradation.

The cost of being wrong on taking action on global warming. Is what, cleaner air. Pregant pause.

An economy moved to a cleaner footing and economic dislocation while it is happening? I don’t remember the resisters giving a shit abut economic dislocation when Ronald Reagan was firing all the air traffic controllers for having the temerity to strike. Or Maggie Thatcher destroying the industrial sector in Britain.

But the carbon tax deniers in Australia?

I think the argument is “we cannot afford to make sure we survive as a species”.

The cost of being wrong the other way?

The End.

Posted in Uncategorized | Leave a comment

Patents, regulation, human behaviour, and Helminthic Therapy

Our mission statement, no I don’t like them either but they are helpful to keep everyone on the same page, is: To change the practice of medicine to incorporate the use of benign infectious organisms to prevent and treat disease, cheaply.

That last word is proving the hardest in a hard task. Everything, and I mean everything, is set up to almost guarantee healthcare is expensive. In this case absurdly.

One of the biggest costs is regulatory approval. By one estimate around a billion dollars for a patent medicine.

Why should an organism we co-evolved with, and that the parasitology texts and CDC say is harmless, one that cannot proliferate within you, one not worth treating in light infections (CDC), be regulated as a drug? Why are none of the outfits with the resources and experience required for developing them as therapeutics (drug companies) doing so?

Patents and control aren’t possible.

Witness the lengths drug companies go to to maintain monopoly profits, (PDF file) the only ones they are interested in, via patented drugs. Drug companies are just companies. Their interests are not in making you well, they are in producing profits. Most everyone agrees this is true, but does anyone look at what it means? (this is your cue to send me a link to something else I don’t want to read, thanks)

The drug companies benefit much more from this set up than they like everyone to think, the most profitable sector of the economy historically, four times as profitable as the average of the rest of the economy, because it is based on the artificial monopoly granted by a patent. Who cares if it costs a billion to get approval, if I can make that annually in profits for 17 years after being granted approval? That it costs a billion is just a barrier to entry and squashes innovation, by protecting the drug companies from competitors. Any industry where a hand of cards costs a billion is not going to have many players. A single hand of cards.

Then there is patent manipulation, the most cynical attempt, it failed mercifully, I read of was that of its’ owners to extend the patent on Subutex. Novel tactics, love it. Nice to see a British company displaying such innovation, too. Go team.

Quite rightly their exists (well, it exists anyway) an enormous regulatory, research and commercial apparatus, that intertwines and interconnects to produce healthcare products, primarily drugs for the last fifty years.

Given the fake cures sold in the past, often sold using fake scientific journals publishing fake studies promoting the efficacy and wonders of the latest product of the drug company that published the journal, this isn’t surprising. Merck say, when it was promoting it’s new drug Cocaine in the late 19th Century. One has to be grateful that all these well educated, earnest people, with it has to be said enormous debts to service for said education, are so devoted to our health in these modern times. I am sure human nature has changed profoundly since the 19 Century.

But has much changed? It costs money to publish your research in the Lancet, et al. I mean, they charge you. Then the journals charge the readers, too, to read your research. Those are publications I don’t think we have to worry about because of the rise of digital media. Or do we? If you can open source software why not peer reviewed publishing of science? Someone must be doing it, that would be something I would be interested in hearing about.

Then there are the medical disasters like Thalidomide, due to something called chirality* by the way, making me glad that drugs are rightly heavily regulated. But helminths, whatever the regulators say, (hey, invent another category to regulate!) are not drugs, and have none of the risky characteristics of a drug. That is, they are not novel molecules never seen before by our bodies, quite the opposite.

Regulation occurs in a weird and sometimes ineffective way, too. Witness Phen-Phen, the COX2 inhibitors, and the Statins (my favourite candidate for a disastrous withdrawal is Gilenya, of the new drugs). What happened with all the checks with those drugs? I seem to remember seeing a calculation that the excess deaths due to just one of the COX2s was 500 Americans a month, and this went on for years, with multiple drugs like it. Lets see, oatmeal, exercise and fewer cheeseburgers, (statins now), or a drug that can make all my muscles die or destroy my liver?

Perhaps numbers like 100,000 deaths due to hospital accidents annually in the US have just made us numb, or perhaps they are too large to really grasp and comprehend. Like the concept of infinity.

Or perhaps we just aren’t paying attention, Facebook and Twitter consume a lot of time, after all. We all need to get laid. Hey, we’re busy.

For instance a company developing a drug can conduct as many studies as it likes, but it does not have to submit the results from all of them. Hold that thought.

Having read a critique of the approval of Claritin, or Loratadine as the generic, which showed that the drug was only 9 points more effective than sugar, aka placebo, at suppressing the symptoms of seasonal rhinitis, one is lead to wonder which studies of that drug got omitted? What about for your heart medication, or for your antidepressant?

Take the ability of the company to be selective about the results it submits, add in positive results bias, and the undoubted corrupt behaviour, unbidden for sure, of scientists who understand upon which side their bread is buttered, and it appears to this commentator that some drugs might not deserve their big profits.

With the share of annual market in Claritin manufactured by it’s original patent holder in the US alone worth $401M in 2010, I say this one is based on bullshit. I should know, I took it long enough, it did bupkiss. If you doubt scientists will whore themselves look only so far as the tobacco industry and it’s scientific apologists. Fantasists might have been better. I don’t recall any apologies.

To get an idea of the scale of the market in just Claritin and it’s generics, see the news on just this drug alone in a typical online source focussed on generic drugs business and economics. If people are writing that many articles about a now generic hay fever pill you better believe there is money in it. And bullshit follows money as sure as night follows day.

We have been approached by a few drug companies, one massive. Their only concern, “are you (we) doing drug candidate identification”? I could make a lot of money in that, I have known that since the beginning. But it is different when your ass is being sniffed by someone with a lot of money. Anyway, we aren’t, so they didn’t, and neither did I.

Then there is the question as to why bother? Keeping it cheap I mean. Philosophically when I started out I was into the idea, I don’t need to be that rich after all, and why the hell not? It seems better for more people.

Thing is I am not sure it is what anyone wants. Even you probably don’t really want it, rational as you are, and smart, and all. Educated, I forgot educated.

First of all people tend to equate price with value or quality, particularly with products like healthcare. Never mind all the rest. I might have been better served charging a hell of a lot more, even by my metric of helping the most people the fastest.

Then there is the issue of having to change the practice of medicine, which means also changing the practice of regulation, in practice that is. It is proving to require a lot of practice.

It is a lot harder than simply introducing a pill, no matter how expensive that is. At least there is a map for that. That and I have never done anything like this before, and, you can depend on it, never will again.

By one estimate in one of the articles above I remember 800-1,200 million USD to replace a prescription drug on patent with a new one. Sell four pills to every American annually at that price for a dollar and you might break even, on R&D. Add in another $400M for marketing and distribution, television advertising (in the US at least), and manufacturing, including capital costs, ongoing regulatory compliance, or the penalties for failing in that respect, and the price per pill rises and rises. Wish I could afford a $3Billion USD fine, I might get to see my kids.

No one wants to do this, keep it cheap I mean. I wonder sometimes why I should. No one evens wants helminths around as a therapeutic. I am old now, 50. I do not get filled with a sense of excitement, interest and wonder considering spending the rest of that life sitting in meetings with over educated assholes from the regulatory bodies, universities, or drug companies.

I was quite rude to the woman at Astra Zeneca, I enjoyed that.

A lot of our clients got sick after emigrating to the west. When they go home they instantly see their colitis or Crohn’s, as one for instance, improve. By instant I mean they say they can feel the change within a few days.

I invariably say “then why not move back home?”. The reply is always associated with money. Apparently you can buy the bowels of a software developer for about $70K a year, which is what I am guessing is the delta in annual income between Silicon Valley and Mumbai.

You could do it as performance art, pay a migrant to sit in America for two decades and rot from the insides because their environment, like Western Europe’s, is so damaged that millions are being killed by environmental degradation already. Who needs to wait for Global Warming to play out, you are dying in droves now because of environmental damage. It just isn’t televised, yet, so perhaps that is the problem we need to solve?

You could even collect a pool of them and bet on the likely outcome, disease wise, before they even developed the diseases. I bet we would be oversubscribed for visas in a trice.

I would put that in the same company I want to start to televise executions. Hard to think of sponsors right away, but gun manufacturers do spring to mind.

Perhaps there is way to make it less tacky, we could sell them special insurance policies perhaps? That is a bet on someone’s health, or death, after all. So we already do it, so don’t get all moralistic on me.

This peculiar, to me, behaviour (the sticking around to be sick for money thing) is mirrored in an exercise I tried with people contacting us to try therapy initially. I did it until I lost interest, no scientific anything here, just an observation. I suggested to all comers for a while that they should try fresh water sources, as in surface water, and a few pinches of dirt, small, each day in their diet. Try that for six months, if you still need worms come back. I genuinely believe that for most it would be sufficient. I’ll admit that the urbanisation of the population in the developed world does present problems of access to fresh water and dirt anyone would want to ingest regularly. See my point about the environment earlier.

I had one taker, he gave it a desultory effort (he didn’t do jack shit) for a couple of months and contacted us again, saying: “I just want to take something, please just send me hookworm.” Which was the consensus view by the way. “Just send me the helminths.”

I have forgotten what I was trying to say at this point. If I sound cynical it is because I am, and I don’t like it either.

I guess what I am saying is that like in Cameroon where poverty guarantees poverty by making everyone corruptible, and therefore corrupt, we are the problem.

Your behaviours and choices guarantee healthcare is more expensive and complicated than it need be. Less effective than it could be. More toxic than it has to be. Because that is what you want.

We evolved for a different environment, it’s not our fault. And don’t worry, we’ll be back there soon enough, if we’re lucky. One way or another.

That’s right, I should have figured this out before I started.

*As I remember it in the small amounts required for the studies the drug was produced in a way to produce a left or right handed version of the molecule. Full scale production produced the opposite chirality, or handedness. Left became right, or right left. No one understood the importance of shape in biochemistry, or no one noticed, or perhaps cared, at that time. The result was birth defects on a massive scale, of the most awful kind.

Posted in Uncategorized | Leave a comment

Coronado Trial Failures, so called, study design, corruption of medical profession

I want to point out that the Coronado Biosciences TSO trials in the United States, and their results, or lack thereof, have nothing to do with our organisms or approach.

We use a profoundly different pair of organisms, with humans as their definitive hosts. They are adapted to us.

TSO has pigs as its definitive host, so our immune system rapidly destroys them. Any beneficial effect comes from the distraction of the immune system by regular dosing. May as well, as usefully, use fleas or scabies or lice, seriously.

Our organisms modulate the human immune system, by secreting molecules that regulate and alter our immune posture and response, particularly to inflammation. They have to maintain their long period of residence in us. TSO last a couple of weeks, then you need a new dose. Not much immuno-modulation there.

Our results are obtained by asking a fundamentally different question than that asked by scientists.

We have always asked, how can we make this individual well by using helminths within safe limits to restore the ecosystems defined by their bodies.

Scientist ask narrow questions so they can isolate and make reproducible results based on controlling for as many variables as possible, and see how things vary in a very narrow range of inspection. Conducting such a study for so little time, is absurd. They must have known this, as Prtichard must in his failed published, and failed unplublished, studies. If you are wondering, the failed unpublished is his asthma hookworm study, they used too few hookworm to produce any real results.

I have shouted enough already about more worms, for more times. But once more, two years, hookworm in an adult healthy male, 125 hookworm with monitoring of population and possible supplemental doses after six to nine months.

Those are rough guides, IBD and Coeliac disease, intestinal allergies/food allergies, are more complex to manage.

Chronic Fatigue and Fibromyalgia symptoms and history indicate the need for special handling.

How about some real science gentlemen, and a real indication of interest in using these organisms therapeutically instead of the sad mill of drug development everyone is so tired of, except the patent holders and their monopoly profits.

I recently learned Weinstock, Lee and Summers are shareholders in Ovamed, and so stand to benefit substantially from Coronado’s success financially, with very large payments due if the trials of Ovamed succeed, so maybe they torpedoed it to sink that large liability.

On a related issue, this link and story did not get enough notice when I published it a while ago, I got it when I closed my membership in WebMD Professional.

http://www.jasper-lawrence.com/what-a-word-means/ and the word is Honorarium, haha.

I was asked “Do you only participate in programs sponsored by pharmaceutical companies when an honorarium is offered?

Meaning a payment to attend, which is corrupt.

Is your doctor only interested in hearing people, in this case drug companies, talk when they are paid to attend?

Perhaps you should ask them?

See our page on Facebook: https://www.facebook.com/autoimmunetherapies

Posted in Uncategorized | Leave a comment

Another great result for Crohn’s, this time in an adult

In his words, edited to remove any identifying phrases or words:

“Today marks exactly (Jasper, while it did not take this long for him to respond, he was slow to respond as I recall, and this should be born in mind by anyone on or considering therapy) days (20 months) since I have taken immunosuppressive medication of any kind. I suffer moderate to severe Crohn’s, since 2006. I dosed with hookworm late 2010 (22 months ago), and twice in 2011. After three doses totalling 150 worms, I estimate that the hookworm alone achieves 85% symptom relief for me. I rejoice at the phenomenal benefit to my life. It would be no exaggeration to call my case a small miracle. I hope to continue to experience this degree of relief.”

No drugs, quite a result, and not atypical.

Posted in Uncategorized | 3 Comments

Only in America! Let’s hope so.

Patent: Further information: Association for Molecular Pathology, et al. v. United States Patent and Trademark Office, et al.

Methods to isolate and detect BRCA1 and BRCA2 (Breast cancer genes) were patented in the United States by Myriad Genetics. (So just so everyone is clear, this company has effectively patented a part of the human genome, human genes. There are lots of examples of this kind of idiocy, including famously a Texas company patenting Basmati Rice and then seeking to prevent Indian & Pakistani growers from selling their rice under the name Basmati any longer in jurisdictions covered by the patent).

This US patent has been challenged by the American Civil Liberties Union. On March 29, 2010, a coalition led by the American Civil Liberties Union ACLU successfully challenged the basis of Myriad’s patents in New York District Court. The patent was invalidated, but the decision was appealed.

On July 29, 2011 the United States Court of Appeals for the Federal Circuit made their decision and ruled that Myriads patents are valid.

Effect on Gene Testing
The conditions of Myriad’s BRCA patent require that the only laboratories legally allowed to test and sequence the genes are the ones affiliated with Myriad. This exclusive control over BRCA testing, guaranteed by the patent, has prevented peer-reviewed validation of the tests provided by Myriad.

Since the BRCA test is marketed directly to the consumer, it is not subject to government oversight by agencies like the FDA.

Without this government review, gene tests must be studied and assessed by scientific colleagues in a peer review. However, the kind of studies needed to validate the tests require access to the BRCA genes, which are protected by Myriad’s restrictive patent. (Is this funny, tragicomic, enraging, befuddling, ludicrous, or just the free-market?)

Thus, without access to the genes (meaning you cannot even study them without paying Myriad a patent license fee, assuming they are willing to grant it, in the USA – like I said, you could not make this up) or the methods used to sequence them, peer review of the test’s effectiveness is virtually impossible. (here I have to disagree, it is impossible unless you pay Myriad for the use of their patents to study their methods to determine if they are actually effective. Genius, I wish I had a patent on you.)

However, the patents have yet to be enforced in Europe, where BRCA research and testing is becoming more widely available, and several laboratories are currently offering their own BRCA testing. The UK firm NewGene offers the test at a very competitive price, to the NHS, its owner, only. (Equally surreal and non-sensical, of course. But cheaper…)

Legal decisions surrounding the BRCA1 and BRCA2 patents hold particular bearing on the field of genetic testing, as the field is relatively young. Until legal guidelines can be applied to the practice of gene testing, progress in the field will likely suffer due to uncertainty. Any decision made regarding the BRCA patents will likely become precedent for future disputes over the use of genes for testing.

via BRCA1 – Wikipedia, the free encyclopedia.

Posted in Uncategorized | Tagged , , | Leave a comment

Facebook Page for Helminthic Therapy

Hi, we have long had a well maintained and regularly updated FB page, fed in part via our Twitter account. It gets a lot of activity, daily, with links to news, etc.,

To visit go here, and if you just want the twitter feed the address is @wormtherapy (@helminthictherapy was too long, as much as I dislike the term worm therapy it was that or nothing.).

I hope you find these resources useful.

Posted in Uncategorized | Leave a comment

Part 4: The Story of “A”

This is, as the title suggests, one in a series of posts, almost entirely derived from emails from her family that they send me periodically to keep us up-to-date.

At the end of this post, and in a few minutes all the others, is a standard block of text with links to each part of the story of this child, as well as some additional information.

———–

From the child’s father:

“It has been over two years now since we began treating Crohn’s disease in our daughter, “A”, using helminthic therapy.

Specifically human whipworm, from Autoimmune Therapies, and she is today doing better then ever. She was around 21 months old when we started helminthic therapy, she had been diagnosed at 14 months of age, and had not responded to any attempted treatment of the disease, except steroids.

She is now over three and a half, and is as happy, healthy, and as beautiful as any parent could want from a child.

Two years ago my wife and I could have only hoped the future should be so bright for her, and us.

A has now taken four doses of the helminths, and each time her condition has only improved.

I can assure you it was not a straight line to good health, but rather a gradual improvement. Like any good, long term investment, there were setbacks along the way. Despite our better judgment, every time there was blood or diarrhea, in the back of our minds, we would wonder if it was the beginning of a major flare, one that would require the drugs we tried so hard to avoid for her.

But the reality was that it never even came close to that. There is no doubt she is doing better now then a year ago, and certainly two years ago. She continues to gain weight, in fact she is 34 pounds, and her stools continue to improve. We have even begun introducing different foods to her diet, with fantastic results.She can play endlessly with her sisters, is as cheerful as could be, and she is even a little chubby, something we’ll take any day of the week over the alternative.

She has not taken any medication for the Crohn’s disease since shortly after she began helminthic therapy.

Suffice to say, treating our little girl with helminthic therapy was the single best decision we could have made, given the circumstance. The treatment has enabled her to live a normal life with Crohn’s disease, rather then one riddled with pain and fatigue, pills, injections, and steroids.

It is not lost on our family, the thought that today we can focus on teaching “A” to read, and swim, and good manners, rarely worrying or even thinking about the fact that she has Crohn’s disease, instead of living in the bleak future we imagined for her, and us, two and a half short years ago.

I’m proud of what we did for her, and we’re thankful to Autoimmune Therapies for the opportunity to do it.”

End of email.

As it happens I am proud too, particularly of those who work with me to do this. I talk a lot, too much perhaps in the past, of the sacrifices my family has made. Far too little has been said about the team working with me.

All, in different ways, are making very considerable sacrifices to be able to make sure people like “A” continue to get the probiotics they need. Our chief scientist, who had a very good career before I came along, has essentially sacrificed that to peruse this. That is just one easy example to identify and explain.

One day soon I hope that it will be possible to acknowledge their courage, the risks and sacrifices they have made, and to do so completely publicly. I am the figurehead for a group of people who are all intelligent, hard-working, dedicated, principled and very high-integrity individuals.

All intelligent enough to not want their name to appear on my blog.

Here’s to hoping that will one day change and their accomplishments and courage can be lauded publicly.

Links to rest of series on “A”

“A” was under 2 years old when diagnosed with Crohn’s Colitis, and the disease appears from the family’s descriptions to have been severe and aggressive. They approached us when the recommendation for treatment from the child’s Gastroenterologist was one of the biologics, either Remicade or Humira, I cannot remember which.

Below are links to each of the four posts, so far, which for the most part are just emails from the child’s dad on “A’s” progress, and his thoughts and observations.

Managing the links between the posts has become cumbersome, so I have created this standard block of links to tie the story together, explain the context if someone happens upon one of the posts and does not realise they are part of a series, and will probably make a static page to aggregate the whole thing.

Part 1: Part 1 of the story of “A”

Part 2: Part 2 of the story of “A”

Part 3: Part 3 of the story of “A”

Part 4: Part 4 of the story of “A”

Posted in Crohn's disease, Jasper Lawrence, juvenile colitis, whipworm | Tagged , , , , , | Leave a comment

What a word means

When I still lived in the US and Sani Abacha was the suddenly dead president of Nigeria, and it was therefore discovered he had looted billions for him and his family from the Nigerian treasury, some of my friends in the US were aghast at the scale of his corruption. Apparently they did not read much international news.

At any rate my comment was “At least their leaders get a decent price”. Which perhaps explains this map. This is a map of world corruption based on perception, opinion.

In this case, in the accompanying image, a screenshot from my unsubscibing from WebMD Professional, as in for doctors, I was asked the reasons for my leaving.

Amongst which is the most interesting: “Do you only participate in programs sponsored by pharmaceutical companies when an honorarium is offered”.

Honorarium, far more mellifluous a word than any alternative.

how drug companies bribe doctors

Unsubscribe screen shot composite from WebMD “Professional”.

Posted in Uncategorized | 1 Comment

The context of helminthic therapy and the environmental diseases it can be used to ameliorate

I want to emphasise that I believe what we are doing exists in a much broader, well-established context.

The diseases we are trying to work with are all environmental in origin. The hygiene hypothesis essentially says that because we have impoverished the environments defined by our bodies by reducing the variety of organisms that populate us, we are getting sick.

Helminthic therapy is an attempt to restore health by remediating the ecosystem formed by the subject’s body. As in the reintroduction of wolves to control deer populations.

I believe that the most important, eventual, outcome of what we are doing will be to get mankind to see that our health is intricately intwined with our environment. That hundreds of millions of people are already sick right now because of anthropogenic environmental change.

That the environment, our ecosystem, is not something up in the sky or separate from us. That it is part of us, and intricately connected with us, our health, our daily lives, that we are component parts of one integrated, dynamic system.

That the ecosystems defined by our bodies and immediate environment, and our daily habits, have been so damaged that hundreds of millions of people are living lives limited by pain, fear and suffering.

If we succeed in that then a profound change in human behaviour towards our planet will occur. Because everyone will be conscious of their direct stake, theirs or their children’s health, in the health of the planet as an immediate phenomena. Not as some distant possibility that we might be able to put off by using the recycling bins.

That there are not ecosystems, except as artificial concepts. There is an ecosystem, and everyone”s health depends on it in profound and immediate ways, because we are all part of it.

We are the ecosystem. I am the ecosystem. You are the ecosystem.

Further, right now, our species in the industrialised and industrialising world, is under enormous selection pressure. Those with MS or Crohn’s, just two instances, will be much less likely to choose to procreate.

Ironically it is likely that many of the diseases we can address with helminthic therapy arise out of genetic adaptation to parasite/microbe rich environments. So in a sense the best adapted specimens, the very latest genetic models of humans, are those experiencing the worst consequences of environmental change.

We are witnessing not just the extinction of various species, but also a strong and rapid change in mankind’s genetic makeup.

I recognise that we should not attempt to “boil the ocean” as a friend used to put it, but I think if we frame this correctly we will find more allies than at first it might appear, and be able to present the concept of what we want to achieve in a more recognisable, and palatable, framework. We can just fit in, perhaps, rather than trying to present something entirely alien. If we are another environmental cause our pool of allies increase, and our messages are easier to understand, fit within a contextual and conceptual framework that is familiar.

That really is it for a while, enjoy your summers. Get outside, get dirt under your fingernails, get some sunshine, and get some river water down your nose.

Posted in ecosystem, helminthic therapy, helminthic therapy research, hookworm, hygiene hypothesis, whipworm | Tagged , , , , | 2 Comments

Hiatus from Posting for a while

Hi, sorry, but we are in the middle of some big activities, including moving.

While that is going on I and my advisory board have decided AIT should stop press contacts and of course blog posts.

Once we have our ducks in a row, and all these new changes, underway and coming soon, I will resume posting and update everyone on all the exciting developments I have had to keep quiet about (difficult for such a blabber mouth like me) for so many months.

I promise it will be worth the wait, but apologise for stopping mid stream like this. Although I have to say we were done with my childhood and adolescence.

So, probably like My Wicked, Wicked Ways, which I think was the title of Errol Flynn’s autobiography, it was about to get a lot more boring anyway.

Meaning, as soon as he got to Hollywood and became famous the book became boring.

On the subject of good autobiographies I can recommend in the same vein The Moon’s a Balloon by David Niven. He did two volumes of autobiographies, and the first was by far the best.

Back soon, take care of yourselves (all three of you).

Jasper

Posted in Uncategorized | Leave a comment